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Analyses
Seeing is
Believing
Explore how our experts can help you.
Visualize your structures with cryo-EM.
3D Reconstruction
NIS expertly deploys cryo-EM and advanced data processing generate high resolution 3D maps and models of challenging molecules. More than half of the structures we've solved are membrane proteins and more than 76% of our structures are below 3.5Å resolution.
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2D Class Averaging
2D classification is a process by which individual particles from TEM images (cryo or NS) are selected, aligned relative to each other, and computationally averaged. 2D classes provide information on particle flexibility, features, as well as on domain structures.
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Negative Stain Screening
Our negative stain screening services provide rapid assessments of particle size, symmetry, morphology, degree of aggregation, conformational and compositional heterogeneity, antibody interactions and higher order structure.
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Encapsulation Efficiency
Encapsulation efficiency is critical in the design of drug delivery systems. Explore how NIS deploys cryo-TEM to demonstrate structural parameters of nanoparticles.
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Particle Morphology & Lamellarity
Cryo-TEM for lamellarity and particle morphology analysis provides important structural details on a per-particle basis that cannot be captured by other methods.
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Particle Size Distribution
Particle size distribution analysis of cryo-TEM images provides precise distribution measurement for nanometer to sub-micron particles in heterogeneous and homogeneous samples.
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Single Particle Analysis
Cryo-EM is widely adopted for drug target structural enablement. Explore our cryo-EM single particle analysis capabilities for your structural biology applications.
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Particle Titer Determination
Determining particle titer and the ratio of empty to fully packaged capsids with cryo-TEM is important for development and monitoring of viral vector preparations.
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