Analyses

Cryo-Electron Tomography (Cryo-ET)

Scientific rendering of 3D protein structure, structural biology | Nano Imaging
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Standard TEM imaging results in 2D projections of 3D objects. This can complicate the interpretation of 3D structure when necessary. While single particle analysis can reveal the 3D structure of small, relatively homogeneous particles, samples consisting of larger and more heterogeneous particles require a different approach. Cryoelectron tomography (Cryo-ET) is a process for generating a 3D volume from a single field of particles.

Types of Proteins We've Imaged

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Nanoparticles We've Characterized

  • Extracellular Vesicles & Exosomes
  • Extracellular Vesicles & Exosomes
  • Lipid Nanoparticles (LNPs), with mRNA, RNA, DNA payloads
  • Lipid Nanoparticles (LNPs), with mRNA, RNA, DNA payloads
  • Liposomes
  • Liposomes
  • Micelles
  • Micelles
  • Polymeric nanoparticles
  • Polymeric nanoparticles
  • Virus-Like Particles (VLPs)
    • Associated Adeno-Virus (AAV) Characterization
    • Hepatitis B Virus (HBV ) Characterization
    • Human Papillomavirus (HPV) Characterization
    • Lentivirus Characterization
  • Virus-Like Particles (VLPs)
    • Associated Adeno-Virus (AAV) Characterization
    • Hepatitis B Virus (HBV ) Characterization
    • Human Papillomavirus (HPV) Characterization
    • Lentivirus Characterization
  • Viruses, attenuated and recombinant (BSL-2 & below)
    • Adenovirus (AV) Characterization
  • Viruses, attenuated and recombinant (BSL-2 & below)
    • Adenovirus (AV) Characterization
  • Protein based nanoparticles
    • Albumin NPs (Abraxane)
    • SARS-CoV-2 subunit vaccine
  • Protein based nanoparticles
    • Albumin NPs (Abraxane)
    • SARS-CoV-2 subunit vaccine

Frequently Asked Questions

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