Analyses

Single Particle Analysis

Scientific rendering of 3D protein structure, structural biology | Nano Imaging
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Single particle analysis workflows.

Single particle analysis (SPA) is a group of related computerized image processing techniques used to analyze images from transmission electron microscopy (TEM). These methods were developed to improve and extend the information obtainable from transmission lectron microscopy (TEM) images of samples and allow for high resolution structure determination of proteins, protein complexes and viruses.

Types of Proteins We've Imaged

  • Antibacterial Targets
  • Antibacterial Targets
  • Antibody-Antigen Complexes
  • Antibody-Antigen Complexes
  • DNA & RNA Editing Enzymes
  • DNA & RNA Editing Enzymes
  • DNA Binding Proteins
  • DNA Binding Proteins
  • DNA Polymerases & DNA Repair
    • POLQ
    • BRCA
  • DNA Polymerases & DNA Repair
    • POLQ
    • BRCA
  • GPCRs
  • GPCRs
  • Icosahedral Viruses
    • Adenovirus
    • Adeno Associated Virus (AAV)
  • Icosahedral Viruses
    • Adenovirus
    • Adeno Associated Virus (AAV)
  • Inflammasome
  • Inflammasome
  • Ion Channels
  • Ion Channels
  • Macromolecular Complexes
    • Ribosome
    • Spliceosome
    • BAF
  • Macromolecular Complexes
    • Ribosome
    • Spliceosome
    • BAF
  • Membrane Proteins
  • Membrane Proteins
  • Protein Degraders
    • PROTACs
    • Molecular Glues
  • Protein Degraders
    • PROTACs
    • Molecular Glues
  • Protein-Nucleic Acid Complexes
  • Protein-Nucleic Acid Complexes
  • Proteins, with & without Ligands
  • Proteins, with & without Ligands
  • Solute Carrier Transporters (SLCs)
  • Solute Carrier Transporters (SLCs)

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Frequently Asked Questions

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