Leading the Revolution: CryoEM-Enabled Drug Discovery
We are open! NIS continues to operate at full capacity with new services & locations to support your protein, vaccine, delivery and antibody projects. #COVID19 projects receive prioritization.

We are the premier industry provider of services, microscope access and training in electron microscopy for pharmaceutical and biotechnology companies.  In recent years, technical advancements in the cryoEM workflow have enabled high resolution structure determination of macromolecules at resolutions previously restricted to X-ray crystallography, NMR and complementary methods. This has opened up whole families of new and important targets previously thought intractable for Structure-Guided Drug Design. 


Our mission is to bring the power of CryoEM to every developer of new therapeutics through a differentiated service offering, making the method accessible and affordable for Discovery teams at all stages of method adoption. Our laboratories are powered by five of the industry's most advanced microscopes, and the industry's most experienced team of microscopists, analysts, and support staff. All of our work is performed with the quality controls and service levels expected of a top tier contract research organization.  


2,000 +

Projects Completed

200 +

Single Particle Projects

60 +

Structures better than 3.5Å

30 +

MicroED Samples Collected

Structural Biology
& Chemistry

Comprehensive cryoEM & microED services for high resolution 3D structure determination.

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Biologics & Drug
Development

TEM analysis for antibody development, gene & drug delivery, vaccine & virus characterization.

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Working
​With Us

Learn about our unique service portfolio, including project-specific proposals, training programs & instrument access.

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Get to know our team

Speak with our experts about using TEM to support your drug discovery efforts.

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