Applications

CryoEM allows the determination of 3D protein structures that are challenging to solve. NIS has many ways to work with clients at all stages of drug discovery.

CryoEM provides insights to a protein's function, role in disease, & how drug candidates bind & interact w/ targets to reveal 3D structures of complex proteins.

MicroED provides high resolution structures for challenging small molecule samples, especially when growing large crystals is challenging.

TEM can provide 3D reconstructions of vaccine particles to visualize structural characteristics, such as homogeneity, size, distribution, purity & aggregation.

Gain understanding of structural characteristics of formulations earlier. Optimizing gene delivery can help focus on the formulations most likely to succeed.

Explore how expertly deployed transmission electron microscopy (TEM) can provide critical structural analyses for manufacturing and QC applications.

Stability of liposomes & nanoparticles is critical. TEM analyses allow direct visualization of particles to monitor size, shape, lamellarity and morphology.

NIS can help you to deploy cryo-TEM to visualize individual particles and simultaneously provide information on size, shape, lamellarity, and encapsulation.