Analyses

3D Reconstruction of Structures

Scientific rendering of 3D protein structure, structural biology | Nano Imaging
NIS Molecule
NIS Protein Structure

Understanding the structure of molecules, such as protein structure, is crucial in determining their function. However, obtaining accurate 3D structures from microscopy images can be a challenging and resource intensive process. Electron microscopy, particularly cryo-EM, has gained a reputation for providing images suitable for building 3D reconstructions. In the right hands, these can be used to create highly informative 3D models.

For 3D reconstructions of a heterogeneous sample, such as a liposome or lipid nanoparticle (LNP), cryo-electron tomography is available.

Types of Proteins We've Imaged

  • Antibody-Antigen Complexes
  • Antibody-Antigen Complexes
  • GPCRs
  • GPCRs
  • Ion Channels
  • Ion Channels
  • Multi-protein complexes
  • Multi-protein complexes
  • Other Membrane Proteins
  • Other Membrane Proteins
  • Other Soluble Proteins
  • Other Soluble Proteins
  • Protein Degraders & Ternary Complexes
    • PROTAC® Degraders
    • Molecular Glues
  • Protein Degraders & Ternary Complexes
    • PROTAC® Degraders
    • Molecular Glues
  • Protein-Nucleic Acid Complexes
  • Protein-Nucleic Acid Complexes
  • Receptors
  • Receptors
  • RNA
  • RNA
  • Solute Carrier Transporters (SLCs)
  • Solute Carrier Transporters (SLCs)

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