Particle Size Distribution

particle size distribution image

Assessment of the size distribution for particles in a given sample is an essential characterization step in pharmaceutical and biotechnology process development, formulation, and production.  Standard nanoparticle sizing methods can be lengthy procedures and/or be prone to bias introduced by contaminants. 

NIS has developed advanced image analysis software for semi-automated particle sizing and contouring that provides precise, statistically determined, and accurate sample size distribution measurement for nanometer to sub-micron particles in heterogeneous and homogeneous sample solutions.  

These analyses help answer questions regarding batch or lot similarities and consistency, biosimilarity, and to reconcile results from size measurements obtained from other methods. This service can be used with negative stain and cryoEM images. 

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