Direct determination of particle morphology is a critical aspect of particle characterization. We evaluate size range, shape, and overall appearance of particles in a sample.
Finer structural details such as presence or absence of membrane bilayers, extent of surface modifications, appearance of particle interiors etc. are also determined. These factors are known to influence biological activity, biodistribution and toxicity. Knowledge of morphological characteristics is essential for accurate pharmaceutical and biotechnology formulation development.
Our automated methods provide reliable high throughput image acquisition and help answer questions on size, shape, lamellarity, cargo load, and surface morphology. This service can be used with both negative stain and cryoEM images.
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