Electron microscopy and related technologies have been used to overcome several challenges associated with vaccine design and vaccine development and the study of viral structures.
One prominent example is how cryoEM was used to conduct semi-automated particle size analysis to characterize the size distribution of Human Papillomavirus-like particles in vivo – in order to help monitor the lot-to-lot consistency of the HPV vaccine Gardasil. Read the whitepaper about Gardasil and virus-like particle (VLP) characterization here.
Hosted by Anette Schneemann, NIS Chief Scientific Officer, our free on-demand webinar will uncover the full analytical toolbox of electron microscopy for viral research and vaccine R&D, including:
- Particle morphology, particle size distribution, and integrity
- Adjuvant interaction
- Epitope mapping
- 2D and 3D structure elucidation
- Antibody interaction
About the Host
Anette Schneemann’s distinguished career in virology has included being Associate Professor in the Cell and Molecular Biology Department at The Scripps Research Institute (TSRI) in California, where her laboratory focused on the structure-function analyses of virus particles. She has extensively worked with structural biologists to determine high and low resolution structures of virus particles and proteins by X-ray crystallography, cryo-electron microscopy and electron tomography.