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| The Challenge: Particle Sizing for Characterization |
| Accurately defining the size distribution of particles in a given sample is essential for characterization during pharmaceutical and biotechnology process development, formulation and production. Methods of particle size determination that rely on Dynamic Light Scattering (DLS) have limited ability to accurately determine size distribution in heterogeneous samples. |
| The Solution: CryoTEM Particle Sizing |
| Using advanced methods developed at NanoImaging Services, particle analysis provides precise, statistically determined, and accurate sample size distribution in heterogeneous and homogeneous samples across a range of 10 nanometers to 1 micron. |
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Samples A and B - CryoTEM images of two preparations of Human Papilloma virus like particles |
Size distribution of sample A (blue line) and B (red line) |
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